Beyond photoaging: additional factors involved in the process of skin aging
نویسندگان
چکیده
منابع مشابه
Overview of skin aging and photoaging.
Aging skin is an issue of concern to many patients. In this review aging and photoaging are defined, mechanisms which underlie these processes explored, and available treatment options discussed.
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Research conducted during the past 25 years has produced an understanding of the mechanisms that lead to connective tissue damage during chronological aging and as a result of chronic, repetitive exposure to ultraviolet (UV) radiation from the sun. While the etiologies of these two conditions are distinct, they share common pathophysiological mechanisms. In both conditions, upregulation of coll...
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Skin aging is not a unique phenomenon but it is commonly divided into two different processes: chronological aging and photo-aging. Therefore we recognise two different phenotypes of skin aging. Chronological aging represents the structural, functional and metabolic changes in the skin that parallel the aging and degenerative changes in other body organs. Photo-aging is a consequence of oxidati...
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The goal of this thesis study was to understand the role of TGF-3 in skin photoaging, especially in solar elastosis. Solar elastosis, the accumulation of elastotic material in the dermal extracellluar matrix, is a major hallmark of photoaging. However, the mechanisms by which UV radiation causes solar elastosis are poorly understood. TGF-3 is a multifunctional cytokine involved in the regulatio...
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We investigated the alterations of major fatty acid components in epidermis by natural aging and photoaging processes, and by acute ultraviolet (UV) irradiation in human skin. Interestingly, we found that 11,14,17-eicosatrienoic acid (ETA), which is one of the omega-3 polyunsaturated acids, was significantly increased in photoaged human epidermis in vivo and also in the acutely UV-irradiated hu...
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ژورنال
عنوان ژورنال: Clinical, Cosmetic and Investigational Dermatology
سال: 2018
ISSN: 1178-7015
DOI: 10.2147/ccid.s177448